Hotels near Mayo Clinic Rochester

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If you visit Rochester, be sure to see Mayo Clinic Rochester, which is a popular spot in Rochester. There are many hotel options near Mayo Clinic Rochester to suit your preferences. You can find many budget hotels near Mayo Clinic Rochester, or places farther away at various price points. Below are the closest hotels to Mayo Clinic Rochester in Rochester, United States of America.

Hotels near Mayo Clinic Rochester

12 nearby hotels 14 Aug 2026 – 15 Aug 2026 · 2 guests

  • Hilton Garden Inn Rochester Downtown

    Hilton Garden Inn Rochester Downtown

    ★★★ (11 reviews) 8.9

    129 m from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $114 per night
  • Hotel Indigo Rochester Mayo Clinic Area By IHG

    Hotel Indigo Rochester Mayo Clinic Area By IHG

    ★★★ (21 reviews) 8.8

    157 m from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $151 per night
  • Kahler Grand Hotel

    Kahler Grand Hotel

    ★★★ (326 reviews) 8

    240 m from Mayo Clinic Rochester

    📶 Free Wi-Fi
    $124 per night
  • Hilton Rochester Mayo Clinic Area

    Hilton Rochester Mayo Clinic Area

    ★★★★ (15 reviews) 8.6

    264 m from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $180 per night
  • Kahler Inn and Suites

    Kahler Inn and Suites

    ★★★ (557 reviews) 8.1

    373 m from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $117 per night
  • TownePlace Suites by Marriott Rochester Mayo Clinic Area

    TownePlace Suites by Marriott Rochester Mayo Clinic Area

    ★★★ (5 reviews) 7.9

    540 m from Mayo Clinic Rochester

    🍳 Breakfast included
    $144 per night
  • Centerstone Plaza Hotel Soldiers Field

    Centerstone Plaza Hotel Soldiers Field

    ★★★ (50 reviews) 9

    553 m from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $117 per night

  • Aspen Select

    ★★ (105 reviews) 8.8

    1.4 km from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $93 per night
  • Homewood Suites by Hilton Rochester Mayo Clinic Area/ Saint Marys

    Homewood Suites by Hilton Rochester Mayo Clinic Area/ Saint Marys

    ★★★ (4 reviews) 8.8

    1.6 km from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $110 per night

  • Med City Inn & Suites Rochester Mayo Clinic Area

    ★★ (10 reviews) 7.8

    1.7 km from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $80 per night
  • Baymont by Wyndham Rochester Mayo Clinic Area

    Baymont by Wyndham Rochester Mayo Clinic Area

    ★★ (83 reviews) 7.9

    1.8 km from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $70 per night
  • Holiday Inn Express and Suites Rochester West-Medical Center By IHG

    Holiday Inn Express and Suites Rochester West-Medical Center By IHG

    ★★ (4 reviews) 8.9

    1.8 km from Mayo Clinic Rochester

    📶 Free Wi-Fi 🍳 Breakfast included
    $100 per night